Insulin sensitivity - Environmental pollutants - Insulin resistance

Initial situation:Female (50 years old), European (living in a large city), always slim, sporty, close to nature, BMI of 21.3, no alcohol, healthy diet and lifestyle, non-smoker, but exposed to countless pollutants. Now MCS + CFS + EBV

And now imagine if I didn't take my own tough, extensive preventive measures to control this elevated genetic “actual state” on my own responsibility, then I would have been overweight long ago and would probably be suffering from massive type 2 diabetes.

CONCLUSION:

Each and every one of us must and should take urgent action on our own responsibility. If you look at the statistics on obesity, you get dizzy.

- Massive increase in recent years

- obesity rates well over 60% in some cases

- high costs for treatment and medication, loss of production and premature retirement amount to almost two trillion US dollars worldwide.

- By 2035, these costs could even amount to over 4.3 trillion US dollars. In Germany alone, the economic costs of obesity amount to just over 100 billion US dollars, which corresponds to around 2.8 percent of national GDP. (1)

Prevention of type 2 diabetes mellitus, i.e. reduction of individual risk factors

We should not succumb to the illusion that a new obesity drug alone could alleviate the dramatic situation.

Personal responsibility and prevention are required!

Physical activity, a healthy lifestyle, a healthy diet and paying attention to chronic overeating (excessive calorie intake/high cholesterol intake, etc.), prevention (keeping an eye on obesity, BMI ≥ 25; obesity), sleep quality, minimizing the risk of periodontitis, special care during pregnancy and, of course, minimizing all pollutants/environmental pollution/intoxications/pesticides (as a task for society as a whole, stricter regulations/regulations, etc.) and much more.

And it doesn't take any great clairvoyance to guess that the GPS of carbohydrates is naturally also affected.

Conclusion:

1. Severely limit your intake of processed carbohydrates

2. eat whole and low-glycemic carbohydrates e.g. whole grains, legumes, oatmeal, barley, apples to better manage your blood sugar fluctuations and promote healthy HDL levels

3. Limit your intake of refined carbohydrates (caution: blood sugar levels and low HDL levels!) e.g. white bread, processed snacks, white rice

4. choose healthy fats e.g. monounsaturated fatty acids and/or omega-3 fats

5. eat a balanced and varied diet

Also bear in mind that cholesterol and plant sterols (Phytosterols)
compete in your intestines for absorption into the micelles. Building a healthy gut microbiome is an absolute must.

The effectiveness (accumulation of plant sterols) of plant sterols can be influenced by genetic variations and cholesterol levels may not fall as desired (caution: risk of coronary heart disease (CHD)).

Last but not least, it is easy to imagine that my GPS also indicates that my probability of accumulating plant sterols is lower, i.e. bad. For me, this means taking this genetic problem (e.g. ABDG8) into account in terms of nutrition.

Conclusion:

1. intake of whole grains, for example. Oats Whole grain products, quinoa

2. avoid refined grain products

3. include nuts, linseed, chia seeds, almonds, lettuce, berries, pulses such as lentils, beans and chickpeas in your diet

(1) Statistiken zum Thema Übergewicht und Adipositas - Statistics on overweight and obesity, Veröffentlicht von Rainer Radtke, 01.02.2024, statista